Revolutionizing Scientific Research
Laboratory Machine Interfacing Systems (LIS)
In today’s fast-paced healthcare landscape, efficiency and accuracy are paramount. Laboratory interfacing systems play a crucial role in streamlining processes and ensuring seamless communication between various medical devices and information systems. In this blog, we’ll delve into the concepts of unidirectional and bidirectional interfacing, their implementation using RS232 and RJ45 cables, and how protocols like ASTM and HL7 enhance interoperability in laboratory environments.
Know The LIS
Machine Interfacing with Lab Equipment

Understanding LIS
Lab interfacing systems serve as the bridge between laboratory instruments, such as analyzers and information systems like Laboratory Information Systems (LIS) or Hospital Information Systems (HIS). These systems facilitate the transfer of data, commands, and results, eliminating manual entry errors and saving valuable time.
Enhancing Interoperability with ASTM and HL7
ASTM (American Society for Testing and Materials) and HL7 (Health Level Seven International) are two widely adopted protocols in healthcare for standardizing data exchange between systems.
ASTM
ASTM protocol defines standards for exchanging clinical and laboratory information. It provides a structured format for transmitting test orders and results, ensuring consistency and interoperability between different systems. By adhering to ASTM standards, laboratory interfacing systems can seamlessly communicate with LIS/HIS systems, regardless of the vendor.
HL7
HL7 is a set of international standards for the exchange, integration, sharing, and retrieval of electronic health information. It defines protocols for messaging, data exchange, and interface specifications. By implementing HL7 standards, laboratory interfacing systems can achieve interoperability with a wide range of healthcare information systems, enabling seamless integration into the broader healthcare ecosystem.
Unidirectional Interfacing
Unidirectional interfacing involves the one-way transmission of data from a source to a destination. In the context of laboratory interfacing, this typically means transmitting test orders or results from the LIS/HIS to the laboratory instrument.

Bidirectional Interfacing
Bidirectional interfacing allows for two-way communication between devices, enabling both data transmission and reception. In the laboratory context, this means not only sending test orders but also receiving results back into the LIS/HIS.

Using RS232, RJ45 and Custom Cable
Implementation using RS232
RS232, a standard for serial communication, is commonly used for unidirectional interfacing in laboratory environments. It employs a serial cable to transmit data between devices. The RS232 protocol defines the voltage levels, signal timing, and data format for communication. By connecting the RS232 ports of the LIS/HIS and the laboratory instrument, test orders can be sent seamlessly, reducing manual transcription errors and speeding up the testing process.
Implementation using RJ45 Cable
RJ45 cables, commonly associated with Ethernet connections, can be used for bidirectional interfacing in laboratory systems. These cables connect devices to a Local Area Network (LAN), facilitating communication between them. By configuring the devices to communicate over the LAN using TCP/IP protocol, bidirectional data exchange can be achieved. This setup allows for seamless transmission of test orders from the LIS/HIS to the laboratory instrument and the return of results back to the information system.
We can interface the following Machine:
- Beckman Coulter Dx800 Bidirectional Analyzer
- Sysmex XN 1000
- Mindray BC1000
FAQ
We Are Here To Help You With Any Questions You May Have
LIS software acts as an intermediary layer that received the data from different Lab Instrument and translates data into a unified format understandable by the Laboratory Reporting Information system (RIS) or laboratory information management system (LIMS).
It uses standardized communication protocols like HL7 (Health Level 7), ASTM (American Society for Testing and Materials), and others to facilitate data exchange between instruments and information systems.
Lab interfacing systems play a vital role in modern healthcare by facilitating the seamless exchange of data between laboratory instruments and information systems. Whether through unidirectional interfacing using RS232 cables or bidirectional interfacing via RJ45 cables, these systems enhance efficiency, accuracy, and interoperability in laboratory operations. By leveraging protocols like ASTM and HL7, healthcare organizations can further optimize their workflows, improving patient care and outcomes in the process.
One-way interfacing involves the transmission of data from laboratory equipment to a computer or controller. This unidirectional flow of information allows researchers to monitor experiments, collect data, and visualize results without manual intervention. Common examples include data loggers, where sensors continuously measure parameters like temperature or pH, and transmit this data to a computer for analysis.
Two-way interfacing, also known as bidirectional interfacing, facilitates communication in both directions between instruments and computers. In addition to data acquisition, two-way interfacing enables control over experimental parameters, allowing researchers to adjust settings and parameters remotely. This advanced capability is crucial in automation and feedback-controlled experiments. For instance, in a closed-loop system, a computer adjusts the parameters of a reaction based on real-time feedback from sensors.
Lab machine interfacing is a sophisticated process that integrates hardware, communication protocols, and software to enable efficient and accurate data exchange and automation in laboratory environments. It enhances productivity, data integrity, and compliance with regulatory standards, making it a cornerstone of modern scientific research and diagnostics.